Natural molecule discovery,
(re)industrialized
Generare is unlocking nature’s untapped potential, translating the complexity of microbial DNA into a scalable platform that can transform drug discovery.
By leveraging cutting-edge biotechnology and data, we are accelerating the identification of new bioactive molecules, for medicine and beyond.
sample
We source microbial strains from the environment, accessing nature’s vast reservoir of bioactive compounds. Evolution selected each of these molecules over millions of years for their ability to hit biological targets.
reveal
Using our unique high-throughput cloning technology, we are revealing new bioactive molecules at unprecedented speed and scale.
harness
Once discovered, we decode the natural function of these molecules to turn them into first-in-class medicine, from antibiotics to cancer therapies.
500
FDA approved drugs
Natural products were once the gold-standard for drug-discovery; penicillin being a prime example. They have led to 500+ anticancer, antibiotics and immunosuppressive drugs.
Bleomycin
Rapamycin
Daptomycin
Vancomycin
Erythromycin
Penicillin
Cyclosporine
Streptomycin
Bleomycin Rapamycin Daptomycin Vancomycin Erythromycin Penicillin Cyclosporine Streptomycin
97%
Untapped
97% of the chemical diversity of microbes remains to be discovered. However, new technology is needed to access them.
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Thanks to Generare's unique cloning scale, large numbers of novel bioactive molecules are made available in the lab for direct bioactivity tests.
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Generare has built the most exhaustive map of the uncharted biosynthetic landscape and has the ability to quickly annotate it with in-house experimental data.
This creates a virtuous circle of discovery because, as we gather more data, we can predict which genes are most likely to yield valuable molecules.
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Natural products remain a prime source for discovering novel modes of actions.
Generare provides its partners with the opportunity to access a large number of these molecules with first-in-class potential.
Generare’s discovery engine
Join the team
Our team is based in Paris, in Le Marais. We are recruiting scientists eager to join this entrepreneurial and industrial adventure to explore the ingenuity of nature.
We are bound to having a positive impact on society and the environment. As part of this commitment, we actively work to address one of the world's most urgent problems: the silent pandemic of antibiotic resistance.
From left to right: Charlotte (Tech), Bismarck (Tech), Nadège, (Senior Tech), Heloise (Scientist), Guillaume (CEO), Anne-Camille (COS), Guido (Engineer), Vincent (CSO), Baptiste (Scientist), Humbeline (Scientist)
